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| Latin Names |
Sanskrit Names |
Hindi Names |
Operculina turpethum
(Linn.) Silva Manso / Ipomoea
turpethum
R. Br. (Convolvulaceae) |
Trivruth,
Triputa,
Nishotra |
Nisoth, Nisotar,
Pitohari |
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| Habitat |
It grows
throughout India up to an altitude of 900 m.
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| Morphology
Description (Habit) |
A large
perennial twiner with milky juice and fleshy branched.
The leaves are very variable in shape; the flowers are
tubular-campanulate, white, in few flowered cymes; the
capsules globose with 4 or less, dull black, glabrous
seeds.
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| Principal
Constituents |
A glycosidic resin.
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| Pharmacology |
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Alcoholic
extracts of the fresh fruits of O.turpethum showed antibacterial activity
against Micrococcus pyogenes var. aurus and E. coli1.
The ethanolic, aqueous and ethereal extracts of O.turpethum
roots showed anti-inflammatory activity against carrageenin induced
rat paw edema as well as cotton pellet induced granuloma and formalin-induced
arthritis in rats. The aqueous extract was found to be the most potent
fraction against all the three models of experimental inflammation2.
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| Toxicity |
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The LD50 of the ethanolic
extract was >1000mg/kg i.p. in mice3.
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| Indications |
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The drug
is used as a purgative.
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| Product
Range |
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Herbolax (LaxaCare).
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| References |
- Wealth of India, 1966, Raw materials, Vol. VII, 96-97.
- Khare, A.K., Srivastava, M.C., Tewari, J.P., Puri, J.N., Singh,
S. and Ansari, N.A. 1982. A preliminary study of anti-inflammatory
activity of Ipomoea turpethum (Nisoth). Ind. Drugs, 19,
224.
- Aswal, B.S., Bhakuni, D.S., Goel, A.K., Kar, K. and Mehrotra,
B.N. 1984. Screening of Indian plants for biological activity.
Part XI. Indian J. Exp. Biol. 22, 487.
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